Scanning Electron and Atomic Force Microscopic Analysis of Erythrocytes in a Cohort of Atopic Asthma Patients—A Pilot Study

Background: Non-communicable diseases are often associated with chronic inflammation, placing patients suffering from these conditions at a higher risk of thrombosis and other complications. The pathophysiology asthma and/or atopic is also linked to which consequently may alter blood parameters including erythrocyte structure function. Methodology: objective this study was evaluate differences in erythrocytes between (n = 30) healthy individuals by evaluating routine haematological parameters; structures axial ratios using light microscopy; membrane elasticity atomic force ultrastructure scanning electron microscopy. Results: findings participants were within normal clinical ranges together significantly levels circulating monocytes (p 0.0066), 0.0004), haemoglobin 0.0057), haematocrit 0.0049) patients. analysis eosin-stained microscopy showed more echinocytes, acanthocytes, ovalocytes compared controls significant difference < 0.0001). Atomic reduced asthmatic 0.001). Ultrastructural visible the group controls. Conclusion: Altered ultrastructural morphology change profile evident influence common complications asthma. impact changes on physiological mechanisms coagulation needs be further elucidated.